BioEndurance™ Super Energy, Vitality, Anti Aging, Antioxidant Formula

BioEndurance™ Acetyl-L-Carnitine(Biosint™), Alpha Lipoic Acid, and CoQ10 Combination Formula

Super Energy, Vitality, Anti Aging & Antioxidant Formula

You will notice a difference in energy levels and general well-being.

BioEndurance™ should be the foundation of your anti aging supplement plan. 

The combination of Acetyl-l-carnitine, Alpha Lipoic Acid and CoQ10 is supported by high-quality research demonstrating consistent health benefits, especially regarding heart health, blood sugar management, gum/oral health and overall anti-aging.

Note: BioEndurance contains only pure pharmaceutical grade raw materials.

The Acetyl-l-carnitine (Biosint™) is manufactured in Italy by Sigma Tau Health Sciences.

The Alpha lipoic acid is pharmaceutical grade pure RS form manufactured in the US.

The CoQ10 is pharmaceutical grade manufactured in Japan and Bioperine is manufactured in the US by Sabinsa Corporation.

This product does not contain any ingredients made in China which is typically where less expensive ALC, CoQ10 (synthetic) and ALA are manufactured.

Biosint™ is a trademark of Sigma-tau HealthSciences.

Other ingredients: Cellulose, Stearic Acid (vegetable source), and Silicon Dioxide. 

About other ingredients

Free of: yeast, dairy, egg, gluten, corn, wheat, sugar, fragrance, and preservatives.

Suggested usage: Take 2 - 3 capsules daily. Consider taking this product in combination with BioSynergy CoQ10 Ubiquinol, Daily Multi, and Vitamin D.

BioEndurance™ Information, benefits, side effects & dosage:

Acetyl-l-carnitine, Alpha Lipoic Acid and CoQ10 - A combination of 3 exceptional nutrients that support your body's cell function as you age. Acetyl-l-carnitine is a stabilized form of the amino acid metabolite L-Carnitine and is utilized in the same manner in the body.

- Acetyl-l-carnitine plays and important role in the transfer and utilization of long-chain fatty acids, which are used in the production of energy.

- Alpha lipoic acid is known as the "universal antioxidant" because of its unique solubility in both water and fat. It has the ability to conserve and prolong the life of vitamins C & E in the body, increasing their effectiveness. Alpha lipoic acid is also an excellent metal detoxifier, particularly for mercury and cadmium, which it binds to and neutralizes for excretion.

- CoQ10 is a vitamin-like compound also called ubiquinone. It is an essential component of cells and is utilized by the mitochondria in the normal process of energy production. It helps convert food into energy at a very basic, cellular level and it is an antioxidant. It's also used as a general anti-aging supplement. Because levels of the compound diminish with age (and with certain diseases), some doctors recommend daily supplementation beginning about age 40.

These three nutrients in combination are extremely effective for prolonging cellular vitality and reducing the ravages of oxidative stress by reducing the body's production of free radicals.

ALC, ALA, and CoQ10 also enhance production of adenosine triphosphate (ATP), which is the chemical form of energy in the body.

ATP has at least two functions related to normal DNA activity: One, it provides the energy DNA needs to move and do its job. Two, ATP also provides what biochemists call "ademine ring" to the very structure of DNA. Without ATP, you can't make DNA, and without certain nutrients, you can't make ATP. These nutrients help repair damaged DNA and make new DNA and genes, which are needed for making new cells for healing and normal growth.

The 3 main popular and effective ingredients in BioEndurance™ when combined work synergistically but are generally sold separately and are expensive!

We have researched prices on these main ingredients when sold separately. Using the lowest prices we could find, here's the breakdown:

Acetyl-L-Carnitine 500 mg x 90 capsules = $41.38 
Alpha Lipoic Acid 200 mg x 90 capsules   = $28.78 
CoQ10 20 mg x 90 capsules                  = $14.99
                                               Total = $85.15

Get all of these ingredients in BioEndurance™ for only $38.97!

You save $46!

BioEndurance™ Benefits

Ingredient Info:

Acetyl-L-Carnitine (ALC)
Acetyl-L-Carnitine, ALC, Acetylcarnitine, ALCAR

Acetyl-l-carnitine is a molecule that occurs naturally in the brain, liver, and kidney. Natural levels of Acetyl-l-carnitine diminish as we age.

Common uses for supplemental Acetyl-l-carnitine:

• To enhance cognition.
• Involved in the metabolism of food into energy.
• Mild mental impairment in the elderly showed a significant improvement of several performances during and after Acetyl-l-carnitine treatment.
• Reports indicate that Acetyl-l-carnitine may be effective in the treatment of dementia.
• Treated Down syndrome patients showed statistically significant improvements of visual memory and attention both in absolute terms and in comparison with the other groups.
• To significantly improve items measuring quality of life.
• Improve both spatial and temporal memory, and reduce the amount of oxidative damage to RNA in the brain's hippocampus, an area important in memory.
• Acetyl-l-carnitine is widely used as an energy supplement in Italy.
• Can dramatically improve mitochondrial function and protect the mitochondria from damage.
• A review of clinical studies shows that ALC may slow the natural course of Alzheimer's disease.10
• In combination with alpha lipoic acid, ALC helps maintain heart muscle function in aging animals.11

Brain

 The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.

Several clinical trials suggest that acetyl-L-carnitine delays onset of ARCD and improves overall cognitive function in the elderly. In a controlled clinical trial, acetyl-L-carnitine was given to elderly people with mild cognitive impairment. After 45 days of acetyl-L-carnitine supplementation at 1,500 mg per day, significant improvements in cognitive function (especially memory) were observed. Another large trial of acetyl-L-carnitine for mild cognitive impairment in the elderly found that 1,500 mg per day for 90 days significantly improved memory, mood, and responses to stress. The favorable effects persisted at least 30 days after treatment was discontinued. Controlled and uncontrolled clinical trials on acetyl-L-carnitine corroborate these findings. 

Fertility

Acetyl-l-carnitine have been shown to enhance the reproductive health of women and men.

L-carnitine improves embryo quality and increases blastocyst development rate in couples undergoing ICSI (Fertility and Sterility, Volume 90, Supplement 1, September 2008)

Acetyl-l-carnitine suggested dosage is 500 mg two to three times daily.

Alpha Lipoic Acid (ALA)

Alpha Lipoic Acid serves as a coenzyme in the energy production process in the cells which can provide quick bursts of energy. Alpha Lipoic Acid is unique in that it is both water and fat soluble witch allows it to enter all parts of the cell to neutralize free radicals. Alpha Lipoic Acid contributes to invigorating mental and physical energy and a reduction in muscle fatigue. Dr. Lester Packer, a leading researcher in the area of antioxidants and a professor of molecular and cell biology at the University of California at Berkeley says "Alpha-Lipoic acid could have far-reaching consequences in the search for prevention and therapy of chronic degenerative diseases such as diabetes and cardiovascular disease" .... "and because it’s the only antioxidant that can easily get into the brain, it could be useful in preventing damage from a stroke".

Common uses for supplemental alpha Lipoic Acid:

• May play a role in controlling blood sugar.
• Important for the production of energy inside the cell by utilizing sugar to produce energy contributing to mental and physical stamina.
• Neutralizes free radicals. Unlike Vitamin C which is water soluble and Vitamin E which is fat soluble, alpha Lipoic Acid is both water and fat soluble which allows it to enter all parts of the cell to neutralize free radicals.
• May help reduce LDL (bad) blood cholesterol.
• May help improve memory.
• Chelates (grabs) heavy metals and binds them reducing these oxidants from blood system.
• Inhibits Glycation which is responsible for accelerated tissue damage.
• Recycles and enhances the effects of other antioxidants such as Vitamin E and Vitamin C.
• Significantly increase survival in rats that have suffered a stroke if given before the stroke occurs.
• Not only does it act as an antioxidant itself, it also stimulates production of glutathione (an antioxidant produced by the body), giving cells a double dose of antioxidant.
• Easily absorbed when taken orally and once inside cells is quickly converted to its most potent form, dihydrolipoic acid.
• Because both alpha lipoic acid and dihydrolipoic acid are antioxidants, their combined actions give them greater antioxidant potency than any natural antioxidant now known.
• Important for regulating aspects of the immune system, in particular immune cells called T-lymphocytes.
• Can dramatically improve mitochondrial function and protect the mitochondria from damage.
• Researchers believe ALA treatment improves endothelium-dependent vasodilation in patients with type 2 diabetes.1
• Alpha Lipoic Acid reduced triglycerides in obese and diabetic rats.2
• Migraine sufferers may be able to reduce the frequency and severity of their headaches by supplementing with lipoic acid.3

ALPHA-LIPOIC ACID MAY HELP REDUCE INFLAMMATION

October 11, 2002. The incidence of inflammatory diseases such as arthritis increases with age. Free radicals promote inflammatory reactions, which antioxidants have been successful at diminishing. Scientists recently stimulated the inflammatory response of white blood cells, resulting in an increase of Intracellular Adhesion Molecule 1 (ICAM-1), which encourages white blood cells to stick to other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent antioxidant, was then added to the mix. Researchers said the acid reduced the activity of ICAM-1 to levels in normal, un-stimulated cells in a dose-dependent manner. It also lowered the activity of NFkB (NFkB can increase the activity of genes responsible for inflammation). According to the study, these changes suggest that alpha-lipoic acid may help reduce the effects of inflammatory diseases such a rheumatoid arthritis and psoriasis.

Suggested dosage for Alpha Lipoic Acid is 200 mg two to three times daily.

CoQ10 (Coenzyme Q10)

CoQ10 is a vitamin-like compound also called ubiquinone. It is an essential component of cells and is utilized by the mitochondria in the normal process of energy production. It helps convert food into energy at a very basic, cellular level and it is an antioxidant. CoQ10 (Coenzyme Q10) is one in a series of ubiquinones, naturally occurring compounds produced in nearly every cell of the body, and was discovered as recently as 1957. This Coenzyme Q10 is the highest quality available and synergistically blended with Bioperinewhich has been demonstrated to aid in absorption.

Common Uses for CoQ10:

• Increase cellular energy.
• Boosts immune system function.
• Support muscle tissue function.
• May enhance physical performance.
• Maintains healthy gums and teeth.
• Can dramatically improve mitochondrial function and protect the mitochondria from damage.
• Coenzyme CoQ10 is made by the same enzyme in your body as cholesterol. So if you take statin, you shut down your production of CoQ10 which is neccesary to make energy for your cells.4
• Women's health study reveals an association between decreased levels of CoQ10 and a greater risk of breast cancer.5
• CoQ10 supplementation improves endothial function in human study possibly lessening the risk of cardiovascular disease.6
• CoQ10 supplementation before exercise increases muscle CoQ10 levels, reduced muscular oxident stress, and may increase the amount of time you can exercise until exhaustion.7
• Supplementation of 300 mg/day of CoQ10 enabled adults to increase their velocity on stationary bike, while reducing fatigue.8
• Pooled data from 12 studies (362 participants) revealed an impressive drop in systolic and diastolic blood pressure (16.6 mgHg and 8.2 mm) with CoQ10 doses ranging from 30-360 mg per day.9
• CoQ10 improves endothelial function in patients with type 2 diabetes in study.12
• Studies report that CoQ10 reduces oxidative stress and improves endothelial function.13, 14
• CoQ10 depletion is associated eith worse outcomes in chronic heart failure.15
• CoQ10 has been shown to stop or slow the progression of Parkinson's disease in a sixteen-month study of eighty people at 1,200 mg a day and no side effects.16, 17

The primary function of CoQ10 (coenzyme Q10) is as a catalyst for metabolism - the complex chain of chemical reactions during which food is broken down into packets of energy that the body can use. Acting in conjunction with enzymes, the compound speeds up the vital metabolic process, providing the energy that the cells need to digest food, heal wounds, maintain healthy muscles, and perform countless other bodily functions. Because of the nutrient's essential role in energy production, it's not surprising that it is found in every cell in the body. It is especially abundant in the energy-intensive cells of the heart, helping this organ beat more than 100,000 times each day. In addition, coenzyme Q10 acts as an antioxidant, much like vitamin C and E, helping to neutralize the cell-damaging molecules known as free radicals.

There are many other claims make for CoQ10 that it slows aging, aids weight loss, and enhances athletic performance.

Biotin

Biotin is a B vitamin that is needed for the formation of fatty acids and glucose, which are essential for the production of energy. It also helps with the metabolism of carbohydrates, fats, and proteins. Biotin is found naturally in food. Good dietary sources of biotin include brewer’s yeast, nutritional yeast, liver, cauliflower, salmon, bananas, carrots, egg yolks, sardines, legumes, and mushrooms. Biotin deficiency may lead to skin rash, hair loss, high cholesterol, and heart problems.

Other supplement related news:

Carnitine Supplement Helps Sperm Swim

By David Douglas

NEW YORK (Reuters Health) - Taking carnitine supplements seems to improve sperm mobility in men with poorly active sperm, a problem known as asthenozoospermia, Italian researchers report.

However, for carnitine to work, tiny structures within the cell called mitochondria must function properly. Mitochondria are important because they provide the energy needed for sperm to move their tail and "swim."

Senior investigator Dr. Carlo Foresta told Reuters Health that "it is well known that in some asthenozoospermic subjects an improvement of sperm (motion occurs) after carnitine administration...However in other asthenozoospermic patients this effect is not present."

To investigate further, Foresta of the University of Padua and colleagues studied 30 asthenozoospermic men divided into two groups depending on whether they had normal or abnormal mitochondria function. The researchers' findings appear in the medical journal Fertility & Sterility.

In patients with normal mitochondria function, movement rose from 29.3 percent before treatment to 41.1 percent after 3 months of carnitine. However, in those with abnormal function, movement held steady at about 24 percent.

Thus, Foresta concluded that carnitine treatment is useful "in ameliorating sperm motility only when optimal...mitochondrial function ... is conserved."

SOURCE: Fertility & Sterility 2005.

BioEndurance™ Side Effects:

If you are taking any prescribed drugs from your physician, please check the drug interaction site listed to the left before taking this nutritional supplement. 

Drug Interactions Are there any drug interactions? A. Didanosine (Depletion or interference) Didanosine is a drug that blocks reproduction of the human immunodeficiency virus (HIV). HIV is the virus that infects people causing acquired immunodeficiency syndrome (AIDS). Didanosine is used in combination with other drugs to treat HIV infection.

BioEndurance™ Dosage:

Take 2-3 capsules daily.

Consider taking this product in combination with BioSynergy CoQ10 Ubiquinol, Daily Multi, and Vitamin D.

BioEndurance™ Reviews:

"I have been using only one per day for about 18 months, and I can remember things I would not have believed possible. The improvement is most marked for short term memory but, oddly, seems to have improved long term memory function, too. Most dramatic illustration: I had to open a safe I had not used for three years. Since I couldn't find the combination written down anywhere, I had to try to remember it. Which I did." J.D. USA

"This product has been so good for me. I am ordering this for my Daughter.Thanks, BLM" B.M. USA

"I just received my BioEndurance today. I have been using the ala/alc in smaller doses( total of 8 pills a day) so I am really looking forward to taking fewer pills. One thing I would tell any one starting these is don't get in a hurry. It was a full month before I could feel any difference, I was getting discouraged. Once I did it was like day and night. Within one week. Thanks so much." L.R. USA

"I THINK THIS IS A GREAT PRODUCT." J.M. USA

"Hi, This is the second time I have ordered this product and I do like it as it seems to increase my overall energy and mental function." J.P. USA

"I am very pleased with this product. The overall improvement in my health has been very noticeable. For your information, I have been treated for Lyme disease 5 times since 1992 and have experienced terrible memory problems. That is my main reason for trying your product. I read about it in the Sunday Magazine from the New York Daily News. I am also under treatment for breast cancer." S.S. USA

"Love this stuff! And it is lots cheaper than buying the ingredients separately. I'm a type 1 diabetic, and this has really helped keep my insulin usage down. Thanks, and keep up the good work!" V.B. USA

"A very logical combination of ingredients!" J.A. Canada

"IT IS THE BEST FORMULA OF ALPHA LIPOIC ACID THAT I HAVE EVER FOUND, THANK FOR A GREAT PRODUCT." B.K. USA

"Hi. I've been taking your BioEndurance for about 6 months now and am very satisfied but that's not all. After reading about your BioDiet Plus product, I started taking one in the morning every day in addition to the BioEndurance x 2 a day. Guess what? I stopped drinking coffee and feel more energetic than I can remember since my 20's (I'm 52 now). Just wanted to let you know." J.S. USA (CA)

"Taking only one BioEndurance capsule per day really increases my energy levels. I also take your Theanine a few times a week, which helps my stress level." C.D. USA

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1. Alpha Lipoic Acid(ALA) treatment on endothelium-dependant vasodilation in patients with type 2 diabetes. Eur J Clin Invest. 2010;40(2):148-54
2. Arch Biochem Biophys. 2009 Feb 20
3. Magis D, Ambrosini A, Sandor P, Jacquy J, Laloux P, Schoenen J. A randomized double-blind placebo-conrolled trial of thioctic acid in migraine prophylaxis. Headache 2007 Jan:47(1):57-2
4. Littarrc G.P., Langsjoen P. Coenzyme Q10 and statins: Biochemical and clinical implications. Mitochonrion 2007, March 27(7)Suppl:S168-74
5. Cancer Epidemiol BioMakers Prev. 2011 Apr 5
6. Atherosclerosis 2011 February 17
7. Cooke M, Iosia M, Buford T, et al. Effects of accute and 14-day CoQ10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008;5:8
8. Mizuno K, Tanaka M, Nozaki S, et al. Antifatigue effects of CoQ10 during physical fatigue. Nutrition 2008 Apr;24(4):293-9
9. Rosenfeldt FL, Haas SJ, Krum H. CoQ10 in treatment of hypertension: a meta-analysis of clinical trials. J Hum Hypertens. 2007 Apr;21(4):297-306
10. Carta A, Calvani M. Acetyl-l-carnitine: able to show the progress of Alzheimer's disease? Ann NY Acad Sci. 1991;640:228-32
11. Hagen TM, Moreau R, Suh JH, Visioli F. Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acety-l-carnitine and/or alpha lipoic acid. Ann NY Acad Sci. 2002 Apr;959:491-507
12. Diabetes Care. 2009Feb19
13. Biofactors 2008;32(1-4):129-33
14. Eur Heart J 2007Sep;28(18):2249-55
15. Molyneux SI, Florkowski CM, George PM, et al. Coenzyme Q10. An independent predictor of mortality in chronic heart failure. J Am Coll Cardiol. 2008Oct.28;52:1435-41
16. Shults CW, et al. Parkinson study group. Effects of coenzyme Q10 in early Parkinson's disease; Evidence of slowing of the functional decline. Arch Neurol. 2004 59(10):1541-1550
17. Young AJ, et al. Coenzyme Q10: A review of its promise as a neuroprotectant. CNS Spectr 2007 12(1):62-68 Review

*The above statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.