L-Theanine Suntheanine™ Natural Anti Anxiety - 100 mg 200 mg

L-Theanine (Suntheanine™) Natural Anti Anxiety Supplement

Pure pharmaceutical grade - Promote Relaxation & Overall Positive Mood

L-Theanine Information, Benefits, Side Effects & Dosage:

BioSynergy’s L-theanine (Suntheanine™) supplement helps promote an alert yet relaxed state of mind without drowsiness and increasing calming alpha brain waves and decreasing stressful beta brain waves.

This brand of L-theanine has been shown in clinical studies to help reduce stress, diminish normal symptoms of PMS, heighten mental acuity and reduce negative side effects of caffeine. 1,2,6-10,13-16,20,22,23

L-theanine is a unique, natural, free form amino acid found exclusively in tea.

Made from the highest quality raw materials with guaranteed potency:

Other ingredients: Maltodextrin, gelatin (capsule). About other ingredients

Contains no: yeast, dairy, egg, gluten, corn, wheat, sugar, starch, salt, artificial color, flavor, fragrance, and preservatives.

Suggested Use: 100 to 200 mg 1 to 3 times daily (suggested times are in the morning and before bed) or as needed depending on stress and anxiety levels. 

L-Theanine (Suntheanine™) Benefits:

Biologically Active - In addition to relaxation, research suggests that L-theanine may:

• Relieve stress naturally. 1,2,7
• Reduce and sooth anxiety and depression. 3,4,5
• Enhance relaxation without drowsiness. 6
• Reduce activation of sympathetic nervous systems “fight-or-fight” response. 7
• Improve learning and mental performance. 6,8
• Improve concentration. 9,10
• Increase attention during long-term difficult tasks. 11
• Improve memory and attention in adults with mild cognitive impairment. 12
• Augment the attention and focusing effects of caffeine. 13-16
• Reduce physical symptoms of caffeine such as headaches and tiredness. 13-16
• Be a neuroprotective, preventing and treating disorders such as Alzheimer’s disease. 17,18
• Protect cardiovascular system through anti-stress effects. 19
• Diminish symptoms of PMS. 20
• Lower blood pressure. 21
• Increase calming alpha waves among other benefits with no known downside. 22,23

Stress and Anxiety

Stress and anxiety are debilitating conditions that can shorten life span while lessening performance, well being, and the enjoyment of life. Stress can impair the ability to perform mentally. It may result in reactions to situations that cause enhanced frustration, hostility or even injury. Stress slowly destroys the immune system, lowering resistance to disease and thus allowing degenerative and opportunistic diseases to occur. Stress is a cause of depression. The entire population is subjected to stress. In a 1998 survey, nearly 65 percent of the adult population indicated that they were under great stress. More than 23 million Americans suffer from anxiety illness.

In double-blind, head-to-head comparison study, investigators compared 200 mg of oral L-theanine with 1 mf alpazolam (XanaxÒ), an anti-anxiety drug that is usually taken in only .25 to .50 mg doses. Results: theanine, but not alprazolem or the placebo, induced relaxing effects that were evident at the initial measurement of whether a person felt tranquil versus troubled. 3

PMS

Studies in cooperation with Taiyo Kagaku Co., The University of Shizuoka, and The Family Planning Institute of Japan have shown that women taking 200 mg L-theanine daily have lower incidence of PMS symptoms. These symptoms include physical, mental, and social symptoms. Overall, a significant alleviation of PMS symptoms by L-theanine was observed.

More L-Theanine Benefits

More L-theanine benefits include its being a mood enhancer and stress reliever without causing sleepiness or drowsiness. When people are under too much stress and anxiety, they can become depressed, experience a loss of well-being and can become vulnerable to infections. This leads many people to take powerful antidepressant drugs, which often come with unpleasant side effects that don’t go away, according to MayoClinic.com. “People under stress can mitigate many of the harmful effects of stress with L-theanine without becoming sedated in the process,” according to Clinical Laboratory Scientist Carolyn Perrini. She also notes that this supplement is extremely safe.

Brain Chemical May Thwart Ravages of Aging: Study

L-theanine appears to have a role in the formation of the inhibitory neurotransmitter Gamma Amino Butyric Acid (GABA). GABA (the antianxiety neurotransmitter) increases the utilization of dopamine (the energizing neurotransmitter) and serotonin (the happy neurotransmitter), playing a key role in the relaxation effect.

NEW YORK (Reuters Health) - A shot of a brain chemical called GABA essentially turned back the clocks in the brains of older monkeys, whose brain function briefly operated at levels normally seen in monkeys less than half their age.

The finding may one day help scientists reverse similar age-related deterioration in the brains of people, according to the report published Friday in the journal Science.

GABA, or gamma-aminobutyric acid, is a messenger chemical that is essential for optimizing how brain cells transmit messages to each other and acts to put a damper on unwanted brain signaling activity, explained the study's lead author Dr. Audie G. Leventhal at the University of Utah School of Medicine in Salt Lake City.

Although GABA's age-related decline has not been documented in humans, a host of studies in mammals, including other primates, suggests that a similar process is at work in people, explained Leventhal.

In the current study, Leventhal's team evaluated how a brain region called the visual cortex in old and young monkeys responds to micro-shots of GABA.

Monkeys between the ages of 26 and 32 -- considered very old for monkeys -- that got GABA directly delivered to their neurons responded to visual patterns, such as flashing vertical and horizontal lines, in much the same way as monkeys aged 7 to 9 years old did, according to Leventhal.

Without GABA delivery, the monkeys' aged brains had more difficulty firing neurons that specifically gauge various aspects of depth perception, motion and color, explained Leventhal. Instead, older monkeys have more random firings that make it difficult to observe visual nuances.

In younger monkeys, GABA had no effect since their brains already had optimal GABA functioning.

"The challenge now is to go and look at a variety of GABA-increasing drugs and see how they influence other areas of the brain" and whether or not they improve brain functions known to decline as people age, such as hearing and memory, said Leventhal.

"It may be that already approved GABA (boosting drugs) have a positive effect on mental decline in the brains of older adults, but nobody has ever looked," he told Reuters Health.

Nonetheless, the findings raise some hope that a general decline in GABA may be correctable, explained Leventhal, who noted that people are born and die with the same nerve cells and more research should be conducted in preserving their function. 22

L-Theanine (Suntheanine™) Side Effects:

Documented Safety - No known cautions or drug interactions. L-theanine is considered to be safe based on its historical use as a component of tea and on favorable toxicology studies. Tea is the most consumed beverage worldwide after water, and has been consumed for thousands of years by billions of people. It is estimated that a heavy tea drinker (6-8 cups daily) will consume between 200 to 400 mg of L-theanine daily.

L-Theanine (Suntheanine™) Dosage:

Suggested Use: 100 to 200 mg 1 to 3 times daily (suggested times are in the morning and before bed) or as needed depending on stress and anxiety levels.

BioSynergy L-theanine can also be poured out of the capsule into water, coffee, tea, juice, etc. as it is quickly and completely dissolved. BioSynergy L-theanine potency is not diminished with heat to at least 120 C (100 C is boiling). BioSynergy L-theanine can be taken with meals or on an empty stomach.

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References:

1. Nathan PJ, et al. The neuropharmacology of L-theanine - a possible neuroprotectoive and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21-30 
2. Kimura K, Ozeki M, et al. L-theanine reduces psychological and physiological stress responses. Biol Psychol. 2007Jan;27(1):39-45 
3. Lu K, Gray MA, et al. The acute effects of L-theanine in comparison with alprozolam on anticipatory anxiety in humans. Hum Psychopharmacol. 2004Oct;19(7):457-65 
4. Yin C, Gou L, et al. Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice. Phytother res. 2011Nov;25(11):1639-9 
5. Heese T, Jenkinson J, et al. Anxiolytic effects of L-theanine -- a component of green tea -- when combined with midazolam in rats. AANA J. 2009Dec;77(6):445-9 
6. Nobre AC, Rao A, et al. L-theanine, a natural constitvent in tea, and it’s effect on mental state. Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-8 
7. Kimura K, Ozaki M, et al. L-theanine reduces psychological and physiological stress responses. Biol Psychol. 2007Jan;74(1):39-45 
8. Dimpfel W, et al. Source density analysis of human EEG after ingestion of a drink containing decaffeinated extract of green tea enriched with L-theanine and theogallin. Nutri Neurosci. 2007 Jan-Aug;10(3-4):169-80 
9. Vuong QV, Bowyer MC, et al. L-theanine properties, synthesis and isolation from tea. J Sci Food Agric. 2011 Aug 30;9(11):1931-9 
10. Wakabayashi C, et al. Behavioral and molecular evidence for psychotropic affects in L-theanine.Psychopharmacology. (Berl). 2011 Aug 23 
11. Gomez-Ramirez M, Kelly SP, et al. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo spatial task. Brain Topogr. 2009 Jun;22(1):44-51 
12. Park SK, Jung IC, et al. A combination of green tea extract and L-theanine improved memory and attention in subjects with mild cognitive impairment; a double-blind placebo-controlled study. J Med Food. 2011 Apr;14(4):334-43 
13. Biol Psychol. 2008 Feb;77(2):113-22 
14. Nutr. Neurosci. 2008 Aug;11(4):193-8 
15. Appetite. 2010 Apr;54(2):406-9 
16. Nutr Neurosci. 2010 Dec;13(6):283-90 
17. Ayoub S, Melzig MF. Induction of Neutral end peptidase (NEP) activity of SK-N-SH cells by natural compounds from green tea. J Pharma Pharmacol. 2006 Apr;58(4):495-501 
18. Kim TI, et al. L-theanine… attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity:…of ERK/p38 Kinase and NF-kappaB pathways. Free Rad Boil Med. 2009 Dec 1;47(11):1601-10 
19. Thayer JF, Yamamoto SS, et al. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factor. Int. J. Cardiol. 2010 May 28;141(2):122-31 
20. University of Shizuoka, Family Planning Institute of Japan study 2002 
21. YokogoshiH, Kao Y et al. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci Biotechnol Biochem. 1995 Apr;59(4):615-8
22. SOURCE: Science 2003;300:812-815.

*The above statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.